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We report a narrow-linewidth laser based on thin-film lithium tantalate (TFLT). The laser is composed of an InP reflective semiconductor optical amplifier gain chip hybrid integrated with a TFLT waveguide external cavity cladded with a silicon oxide extended Bragg grating. The single-frequency laser device achieves an on-chip output power of approximately 26 mW and an intrinsic Lorentzian linewidth of ~94 Hz. These results highlight the great potential of TFLT for integrated photonic laser applications, enabling high-coherence and high-power laser sources in a compact platform. 

While strategies involving a 2e − transfer pathway have dictated glycosylation development, the direct glycosylation of readily accessible glycosyl donors as radical precursors is particularly appealing because of high radical anomeric selectivity and atom- and step-economy. However, the development of the radical process has been challenging owing to notorious competing reduction, elimination and/or S N side reactions of commonly used, labile glycosyl donors. Here we introduce an organophotocatalytic strategy through which glycosyl bromides can be efficiently converted into corresponding anomeric radicals by photoredox mediated HAT catalysis without a transition metal or a directing group and achieve highly anomeric selectivity. The power of this platform has been demonstrated by the mild reaction conditions enabling the synthesis of challenging α-1,2- cis -thioglycosides, the tolerance of various functional groups and the broad substrate scope for both common pentoses and hexoses. Furthermore, this general approach is compatible with both sp 2 and sp 3 sulfur electrophiles and late-stage glycodiversification for a total of 50 substrates probed.